We investigate the biological function of small cationic host defense peptides (cathelicidins and defensins) secreted by white blood cells and the epithelial cells in mammals.
The main focus is to discover the underlying mechanisms of cathelicidins and defensins which show to have an important beneficial role in tissue homeostasis, including regulation of harmful inflammation and control of microbial pathogens.
The goal is to advance cathelicidins and defensins (either synthetic derivatives or induction of endogenous production) as natural, efficacious and cost-effective alternatives to current treatments that could reduce the use of conventional antibiotics. This innovation will also benefit the community by reducing economic losses in animal production, improving animal welfare and promoting an environmentally friendly public image for the industry. [https://www.cobolab.com/pi-eduardo-r-cobo](https://www.cobolab.com/pi-eduardo-r-cobo)
Source : Open Agenda
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