Genomic aspects of oncogenesis (Genome organisation and the cell cycle, Chromatin & epigenetics, Gene expression: from transcription to translation, Mutagenesis & genomic alterations)
The ~ 100 imprinted genes in mammalian genomes are mono-allelically expressed based on their parental origin (i.e. they are only active on the chromosome…
Dominique Gagliardi, Institut de biologie moléculaire des plantes, Strasbourg
Abstract: One of the conserved pathways for RNA degradation in eukaryotes, NMD, is triggered by a translating ribosome that encounters a premature termination…
Le rôle physiologique et les voies de dégradation des ARN médiée par l’Exosome reste encore à éclaircir chez les archées, et notamment chez les archées…
Circular RNAs (circRNAs) result from the covalent ligation of the 5' and 3' free ends of linear RNA, making them more resistant to exonucleases and therefore…
Abstract: Hyperthermophiles are exclusively archaea and bacteria that thrive under extreme high temperatures with some species tolerating temperatures higher…
This thesis focuses on HAN, a member of the DHH superfamily, initially proposed to participate in DNA replication fork restart through its interaction with…
Mouse Cortex development
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