Understanding DNA Repair: Visualizing Tumour Suppressors in Action.
The genome is constantly threatened by damaging agents, and accumulated damage can lead to cancer and other genetic disorders. Cells have evolved an intricate…
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Multi-omics dissection of 3D chromosome structure perturbations in patient-derived cells: lessons from imprinting disorders
The ~ 100 imprinted genes in mammalian genomes are mono-allelically expressed based on their parental origin (i.e. they are only active on the chromosome…